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Rao, Tentu Nageswara
- Forced Degradation Study of Terbinafine HCl by HPLC with PDA Detector
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Authors
Affiliations
1 Department of Chemistry, Krishna University, Machilipatnam, A.P., IN
2 Department of Chemistry, SVKP & Dr. K.S Raju Arts & Science College, Penugonda, A.P, IN
3 Department of Animal Science, Chonbuk National University, Jeonju, KP
4 Department of Chemistry, DLR PG College, G. Mamidada, AP, IN
1 Department of Chemistry, Krishna University, Machilipatnam, A.P., IN
2 Department of Chemistry, SVKP & Dr. K.S Raju Arts & Science College, Penugonda, A.P, IN
3 Department of Animal Science, Chonbuk National University, Jeonju, KP
4 Department of Chemistry, DLR PG College, G. Mamidada, AP, IN
Source
Asian Journal of Research in Chemistry, Vol 9, No 11 (2016), Pagination: 561-565Abstract
A simple and inexpensive method was developed with high performance liquid chromatography with PDA detection for determination of Terbinafine HCl and related impurities. The chromatographic separations were achieved on (150×4.6 mm), 5.0 μm make: YMC-Pack ODS-AM, 120A column employing Acetonitrile: methanol and Water pH 7.5, in the ratio of 20:10:10 v/v/v as mobile phase with gradient programmed at flow rate 1.0 mL/min was chosen. Three impurities were eluted within 35 minutes. The detector wavelength of 230 nm was employed.Keywords
Forced Degradation, HPLC, Method Validation, Terbinafine.- Evaluation of Residues of Chlorpyrifos and its Metabolite in Green Apples
Abstract Views :514 |
PDF Views:5
Authors
Affiliations
1 Department of Chemistry, Krishna University, Machilipatnam, Andhra Pradesh, IN
2 Department of Organic Chemistry, Gayathri PG College, Vizianagaram, Andhra Pradesh, IN
1 Department of Chemistry, Krishna University, Machilipatnam, Andhra Pradesh, IN
2 Department of Organic Chemistry, Gayathri PG College, Vizianagaram, Andhra Pradesh, IN